Game: NFL Week 16 ✅ San Francisco 49ers vs Arizona Cardinals Preview, Handicapping, Analysis, Stats, NFL Betting Odds & Lines, 49ers vs Cardinals Picks & 49ers vs Cardinals Predictions
Date: Saturday, Dec 26, 2020
Start time: 4:30 PM EST, State Farm Stadium, Glendale
TV Channel: Prime Video
49ers vs Cardinals 12/26/20 Odds
Best Arizona Cardinals Lines: -5 (-110) Spread – XBET
Over/Under 48 : – BETNOW
San Francisco 49ers will play against Arizona Cardinals in week 16 on Saturday.
49ers vs Cardinals 12/26/20 Betting Prediction
The San Francisco 49ers are clearly in a bad position right now. They lost 6 of their last 7 games and currently stand at 5-9. As inconsistent as they are, things do not get better on the injury list. The whole year has been a nightmare for them and they always have some key players missing games. HC Kyle Shanahan has most probably taken down his faith from QB Jimmy Garoppolo who proved that he can’t lead a team without a rushing game and proper defense.
The Arizona Cardinals, on the other side, have one of the most exciting young teams in the league. They are still struggling as their offense is basically based on the Murray-Hopkins connection and when that is missing, they do not have much to be happy about. Thankfully, their rushing game is also helping the QB-WR duo by all means as Kyler Murray is one of the team’s leading rushers with just 100 yards less than RB Kenyan Drake.
Even though the Cardinals might struggle at some points of the ball game, I still think they will cover. They have something to play for and their offense is amazing. They tend to struggle against dual-threat QBs but 49ers QB Nick Mullen is not one of them.