Game: NFL Thanksgiving ✅ Buffalo Bills vs New Orleans Saints Preview, Handicapping, Analysis, Stats, NFL Betting Odds & Lines, Bills vs Saints Picks & Bills vs Saints Predictions
Date: Thursday, Nov 25, 2021
Start time: 8:20 PM EST, Caesars Superdome, New Orleans
TV Channel: NBC
Bills vs Saints 11/25/21 Odds
Best New Orleans Saints Lines: +6 (-110) Spread – XBET
Over/Under 45 : – BETNOW
Buffalo Bills will play against New Orleans Saints on Thanksgiving at Caesars Superdome, New Orleans.
Bills vs Saints 11/25/21 Betting Prediction
The Buffalo Bills are an interesting story this season. They really struggle and we no longer know what to expect from them, especially on the road. 3 weeks ago, Buffalo scored just 6 points against the plain bad Jaguars. Last week, they lost 41-15 at home against the Colts and that was the least they could get away with. QB Josh Allen threw 2 interceptions and Buffalo committed 4 turnovers as a whole. Indianapolis basically ran over the Bills and RB Jonathan Taylor finished the game with 185 rushing yards and 2 TDs on 32 carries.
The New Orleans Saints are 5-5 and on a 3-game skid. They lost to the Falcons, Titans, and Eagles consecutively. QB Jameis Winston is definitely missing this one and we will see QB Trevor Siemian once again. He is completing just 56.9% of his throws for 920 yards, 8 TDs, and 2 INTs. The coaching staff is trying to get the running game going but without much success so far this season. The Saints are averaging 117.9 rushing yards per game which are good for the 13th best in the league.
Buffalo will definitely score points here as they will face a weak defense. Having this in mind, QB Trevor Siemian will be asked to throw the football a lot and Buffalo possesses the second-best passing defense in the league. This will lead to turnovers and the Bills will finally get over the hump.
Bills vs Saints 11/25/21 Pick
Buffalo Bills -6 (-110) Spread at