Game: NFL Week 10 MNF ✅ Los Angeles Rams vs San Francisco 49ers Preview, Handicapping, Analysis, Stats, NFL Betting Odds & Lines, Rams vs 49ers Picks & Rams vs 49ers Predictions
Date: Monday, Nov 15, 2021
Start time: 8:15 PM EST, Levi’s Stadium, Santa Clara
TV Channel: ESPN
Rams vs 49ers 11/15/21 Odds
Best San Francisco 49ers Lines: +3½ (-110) Spread – XBET
Over/Under 49 : – BETNOW
Los Angeles Rams will play against San Francisco 49ers on Monday Night Football at Levi’s Stadium, Santa Clara.
Rams vs 49ers 11/15/21 Betting Prediction
The Los Angeles Rams are 7-2 and are coming off one of their rarest losses this season. They fell to the Titans 28-16 in a game where QB Matt Stafford did not play at his best. Nothing seemed to be working for HC Sean McVay as the Rams had 2 turnovers and allowed a team that is playing without their best offensive player to score 28 points. The good thing was that Los Angeles managed to outscore the Titans 347-194 yards but they were really ineffective near the end zone.
The San Francisco 49ers are 3-5 and their recent games have been awful. Except for their win against the Bears two weeks ago, they lost each of their other 5 games in the last 6 weeks. The 49ers are still winless in a division rivalry as they lost twice to the Cardinals and once to the Seahawks. The 49ers’ offense is decent, averaging 23.1 points per game but not as good as the fans would have liked.
The Los Angeles Rams are coming off a loss and they usually manage to bounce back in style in such cases. After they lost to the Cardinals this year, they then beat the Seahawks on the road and I expect the same thing to happen this time as well. HC Sean McVay is a great offensive mastermind and he will definitely get QB Matt Stafford out of trouble on Monday and mix the passing game with rushing to win the game.
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Rams vs 49ers 11/15/21 Pick
Los Angeles Rams
-3½
(-110) Spread at 
