Game: NCAAF Week 12 ✅ Louisville Cardinals vs Duke Blue Devils Preview, Handicapping, Analysis, Stats, NCAA Football Betting Odds & Lines, Louisville vs Duke Picks & Louisville vs Duke Predictions
Date: Thursday, Nov 18, 2021
Start time: 7:30 PM EST, Wallace Wade Stadium, Durham, NC
TV Channel: ESPN
Louisville vs Duke 11/18/21 Odds
Best Duke Lines: +20 (-110) Spread – XBET
Over/Under 60½ : – BETNOW
Louisville will play against Duke on Thursday at Wallace Wade Stadium, Durham, NC.
Louisville vs Duke 11/18/21 Betting Prediction
Louisville is 5-5 and mixing good with bad performances every week. You don’t really know what face of the Cardinals you’re going to see. Last week, they were really dominant against Syracuse, beating them 41-3. QB Malik Cunningham had an effective passing game as he finished with 209 passing yards and 4 TDs on 13 for 18 passing. RB Jalen Mitchell finished the game with 102 rushing yards on 15 carries.
Duke is 3-7 and currently on a 6-game losing streak. This losing streak includes losses against ranked sides such as Wake Forest and Pittsburgh. But what we can get from this losing streak is that Duke’s defense is really bad. It allows 36.8 points per game which is one of the worst records in football. The offense mainly relies on rushing the football with the team, averaging 191.8 rushing yards per game.
Louisville has a decent defense against the rush, allowing just 139.3 rushing yards per game. This can well be the decider as Duke really struggles to do anything through the air on offense if the Cardinals are trailing in the game. Most of Duke’s losses are also by more than 20 points.
Top Sportsbooks to Bet on NCAAF
Louisville vs Duke 11/18/21 Pick
Louisville -20 (-110) Spread at 
