Game: NFL Week 13 MNF ✅ Buffalo Bills vs San Francisco 49ers Preview, Handicapping, Analysis, Stats, NFL Betting Odds & Lines, Bills vs 49ers Picks & Bills vs 49ers Predictions
Date: Monday, Dec 7, 2020
Start time: 8:15 PM EST, State Farm Stadium, Glendale
TV Channel: ESPN, ABC
Bills vs 49ers 12/07/20 Odds
Best San Francisco 49ers Lines: -1 (-110) Spread – XBET
Over/Under 47 : – BETNOW
Buffalo Bills will play against San Francisco 49ers in week 13 on Monday Night Football.
Bills vs 49ers 12/07/20 Betting Prediction
The Buffalo Bills continue to impress this season. They had their downs during mid-season when they lost to the Titans and the Chiefs consecutively but these losses were somehow expected. It seems that they struggle when they have to face overachieving offenses and they can rarely outscore them. Still, they proved me wrong on this one against the Seahawks when they beat them 44-34. QB Josh Allen is completing 69% of his passes for 3028 yards, 22 touchdowns, and 8 interceptions.
The San Francisco 49ers definitely have more issues than the Bills. They are 5-6 and are on the verge of missing out on the playoffs. They lost 3 of their 4 games against Seattle, Green Bay, and New Orleans and only beat the Rams. Head coach Kyle Shanahan has most probably moved on for good from Jimmy Garoppolo and Nick Mullens took charge this season. Even though there is a lot more to be expected from the offense, it is still decent, being ranked 12th in passing yards and 16th in rushing yards.
To me, there are a lot of things that are going in the wrong direction right now for San Francisco. Buffalo has the better QB and the better roster as a whole. The 49ers will struggle against the tough Buffalo defense and the Bills can get an early lead which will lead to erroneous throws from Nick Mullens.
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Bills vs 49ers 12/07/20 Pick
Buffalo Bills +1 (-110) Spread at 
